Main Application Scenarios
1. Cardiovascular Protection Research
Hexarelin exhibits broad-spectrum cardioprotective activity, independent of its GH-promoting effect. Studies have shown that hexarelin can:
Improve cardiac function: Acute intravenous administration (2 µg/kg) rapidly increases left ventricular ejection fraction (LVEF), cardiac output, and cardiac index, while reducing pulmonary artery wedge pressure;
Anti-myocardial apoptosis: Significantly reduces angiotensin II and doxorubicin-induced cardiomyocyte apoptosis and improves cell survival;
Reduce ischemia-reperfusion injury: In animal models, hexarelin significantly reduces infarct size and protects myocardial electrophysiological properties;
Inhibit cardiac fibrosis: In spontaneously hypertensive rats, hexarelin treatment significantly reduces myocardial collagen deposition and improves left ventricular hypertrophy and diastolic dysfunction.
2. Skeletal Muscle and Anti-aging Research
Hexarelin also shows potential in studies of age-related muscle function decline. Studies have found that chronic administration of hexarelin can partially restore the kinetic properties of sodium channels in skeletal muscle of aged rats and restore the firing capacity of fast-twitch muscle fibers, providing experimental evidence for its application in aging rats with GH deficiency. Furthermore, hexarelin has been observed to reduce muscle atrophy and promote muscle regeneration in cachexia and sarcopenia models.
3. Endocrine and Metabolic Regulation
As a highly effective GH secretagogue, hexarelin is widely used in neuroendocrinology research to explore the regulatory pathways of GH release and its interactions with hormones such as GHRH and somatostatin.
Storage and Usage
Storage Conditions
Lyophilized Powder: Although stable at room temperature for 3 weeks, long-term storage below -18°C and kept dry is recommended.
Reconstituted Solution: Can be stored at 4°C for use within 2-7 days; for long-term storage, aliquoting and storage at -18°C are recommended, avoiding repeated freeze-thaw cycles. To extend shelf life, carrier proteins (such as 0.1% HSA or BSA) can be added.
Recommended Usage
Reconstitution: Resolve the lyophilized powder in sterile water for injection or a suitable buffer (such as PBS). It is recommended to prepare a stock solution with a concentration of at least 100 µg/mL.
Route of Administration: Subcutaneous injection (s.c.) is a common route of administration. Literature reports a dosage range of 80–160 µg/kg/day in animal studies. The specific dosage needs to be optimized based on the experimental design and research objectives.
Why Choose Us
As the source manufacturer of Hexarelin raw materials, we have the following core advantages:
Professional Production Equipment: We utilize the mature Fmoc solid-phase peptide synthesis (SPPS) technology route, relying on standardized production processes to ensure the process stability and reproducibility of each batch of product.
Stable Supply: As a direct manufacturer, we have a complete production plan and sufficient capacity, enabling us to provide continuous and reliable supply guarantees for research and industrial customers, meeting the needs of different scales.
High Purity and Stable Quality: Through a rigorous quality control system including high-performance liquid chromatography (HPLC) and mass spectrometry (MS), we ensure that the product purity meets standards and that there are minimal batch-to-batch variations.
After-sales Guarantee: We provide professional technical support and after-sales service, offering reliable guarantees throughout the entire process, from product consultation to usage guidance.
FAQ
Q: Where are your products manufactured?
A: Our products are from Shenzhen, China.
Q: What is the minimum order quantity?
A: The minimum order quantity is 10 bottles/set.
Q: How long does it take to ship?
A: In-stock orders will be shipped within 24 hours.
Q: What purity level can you provide?
A: Standard purity 99%.
Q: Which courier service do you use?
A: We offer FedEx, DHL, UPS, and postal services.
Q: How long does shipping take?
A: Approximately 10-15 days.
Q: Can you provide a COA (Certificate of Authorization) quality inspection report and HPLC (High-Performance Computing) report?
A: Yes, all goods undergo professional testing before shipment.
Q: Do you support OEM branding?
A: We support OEM branding services, subject to meeting the minimum order quantity requirement.
Q: How are after-sales services handled?
A: After the customer signs for the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to the service principle of pragmatism and responsibility, actively respond to and properly handle all kinds of issues, without shirking responsibility or avoiding problems, and do our best to protect the rights and interests of our customers.
Q: What payment methods are available?
A: We support bank transfer, Bitcoin, Transferwise, and Xoom.
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