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PEG-MGF 2mg/vial For Musculoskeletal Repair And Regeneration CAS: 108174-48-7.

PEG-MGF 2mg/vial For Musculoskeletal Repair And Regeneration CAS: 108174-48-7.

PEG-MGF (Pegylated Mechano Growth Factor) is a polyethylene glycol-modified form of mechanotroph (MGF), a splice variant of the insulin-like growth factor-1 (IGF-1) gene. MGF is a growth factor specific to muscle tissue, whose main function is to stimulate the division and proliferation of myoblasts and promote the fusion and maturation of muscle fibers—a crucial process in adult muscle growth.

Product Introduction

Application Scenarios

1. Muscle Regeneration and Repair Research
PEG-MGF is widely used in experimental models for skeletal muscle regeneration, hypertrophy, and injury repair. Its sustained bioactivity facilitates the study of satellite cell activation, myoblast proliferation and differentiation, providing molecular-level insights into muscle plasticity, injury recovery, and mechanical stimulation adaptation mechanisms.

2. Cell Signaling Pathway Analysis
As a tool molecule for growth factor signaling research, PEG-MGF can be used to analyze the complex signaling network regulated by IGF-1 subtypes, including receptor-mediated activation, downstream kinase cascades, and gene expression changes, helping to elucidate the unique contribution of MGF in cellular adaptation and tissue remodeling.

3. Tissue Engineering Research
PEG-MGF is integrated into biomaterial scaffolds and cell culture systems to evaluate its effects on cell proliferation, migration, and matrix remodeling. Its prolonged activity supports long-term research, aiding in the optimization of scaffold design for engineered muscle constructs and the development of bioactive materials.

4. Peptide Stability and Pharmacokinetic Modeling

PEG-MGF is a model system for studying the effects of polyethylene glycol (PEG) modification on peptide pharmacokinetics and stability. It is used to assess how chemical modifications affect peptide solubility, enzymatic resistance, and biodistribution.

 

 

Storage and Usage

Storage Conditions

Lyophilized Powder: Store at -20°C or below, protected from light and kept dry.

Reconstituted Solution: It is recommended to aliquot and store at -70°C, avoiding repeated freeze-thaw cycles.

Usage Method

Dissolving: Reconstitute with sterile water or a buffer solution, gently swirling until completely dissolved. Do not vortex.

Filtration: If aseptic treatment is required, filter using a 0.22 µm filter membrane.

Allowing: It is recommended to aliquot into single-use doses to avoid repeated freeze-thaw cycles affecting product activity.

Note: This product is for laboratory research use only and must not be used in humans or for clinical treatment.

 

 

Why Choose Us

In the field of peptide research, the quality of raw materials directly determines the reliability and reproducibility of experimental data. As a direct supplier from the source factory, we provide end-to-end quality assurance from synthesis to delivery:

✅ Source Factory, Controllable Costs
Our own production base eliminates intermediaries, ensuring competitive pricing and supply transparency. Every batch is traceable to raw material procurement and synthesis records.

✅ Professional Production Equipment, Leading Technology
Equipped with advanced solid-phase peptide synthesis (SPPS) systems, high-performance liquid chromatography (HPLC) purification platforms, and precision mass spectrometry (MS) analysis instruments. Mature PEGylation modification technology and controllable PEG molecule linking sites ensure product homogeneity and structural accuracy.

✅ Stable Supply, Ample Inventory
Large-scale production capacity combined with scientific inventory management guarantees stable delivery times for both small-batch research orders and large-scale long-term purchases, ensuring uninterrupted supply and no delays.

✅ Purity ≥99%, Superior Quality
Each batch undergoes HPLC purity testing and mass spectrometry molecular weight confirmation, with purity consistently maintained at ≥99%. We provide batch-specific Certificates of Analysis (COA), ensuring verifiable data and laying a solid foundation for your research.

✅ Stable Quality, Consistent Batch Quality

We strictly adhere to standardized SOP operating procedures, controlling temperature, time, and quality throughout the entire process from amino acid raw material input to final freeze-dried product, ensuring high consistency in physicochemical properties and biological activity between different batches.

✅ Guaranteed After-Sales Service, Professional Support

We have a professional technical support team providing product consultation, storage guidance, and technical documentation support. In case of any quality issues, we promise a rapid response and proper resolution, ensuring worry-free purchasing.

 

 

FAQ
Q: Where are you located?

A: Our products are from Shenzhen, China.

Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity levels can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Liquid Chromatography) test report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM branding?

A: OEM branding service is supported, subject to minimum order quantity requirements.

Q: How is after-sales service handled?

A: After the customer signs for the goods, if a quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting the rights and interests of our customers.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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