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MGF 2mg/vial Is Used For Tendon And Ligament Repair And Myocardial Protection.

MGF 2mg/vial Is Used For Tendon And Ligament Repair And Myocardial Protection.

MGF, short for Mechano Growth Factor, also known as IGF-1Ec, is a splice variant of the insulin-like growth factor-1 (IGF-1) gene. This molecule is specifically upregulated in muscle tissue when subjected to mechanical stress (such as resistance training, stretching, or injury), and is a key "first responder" in initiating local tissue repair signals. Natural MGF contains a unique E-domain at its C-terminus. This sequence makes it significantly different from systemic IGF-1 in function: MGF does not directly activate the classical IGF-1 receptor, but rather exerts its local cellular protective and repair regulatory effects through non-classical signaling pathways (possibly involving nuclear signal transduction).

Product Introduction

Main Application Scenarios

Application Areas

Skeletal Muscle Regeneration Research: Sports injury repair, satellite cell proliferation dynamics, Sarcopenia mechanisms

Bone Repair Research: Osteoblast proliferation, bone defect healing, accelerated fracture repair (rabbit model shows healing levels reaching the control group's 6-week level in 4 weeks)

Cardioprotective Research: Myocardial ischemia-reperfusion injury, cardiomyocyte apoptosis inhibition, cardiac stem cell recruitment

Neuroprotective Research: Peripheral nerve injury, nerve survival and myelin regeneration under hypoxic/inflammatory conditions

Tendon and Ligament Research: Anterior cruciate ligament (ACL) fibroblast migration and adhesion, collagen synthesis regulation

Cartilage Repair Research: Chondrocyte migration, bone marrow mesenchymal stem cell (BMSC) differentiation into chondrocytes

Aging-Related Research: Age-related decline in MGF expression mechanisms, satellite cell depletion and muscle loss

Note: MGF/PEG-MGF is currently a research use only chemical and has not yet been approved by the FDA for routine human treatment. Existing evidence mainly comes from preclinical animal models and in vitro cell studies; human clinical trial data remains very limited.

 

 

Storage and Usage Instructions

Lyophilized Powder: -20°C (frozen) 12–24 months. Protect from light, moisture, and seal tightly; avoid repeated freeze-thaw cycles.

Short-term Storage: 2–8°C (refrigerated) 6–12 months. Suitable for batches intended for immediate use.

Reconstituted (sterile water): 2–8°C (refrigerated) 28–30 days. Store protected from light; discard immediately if turbidity or precipitation occurs.

Reconstituted (sterile water): 2–8°C (refrigerated) 48 hours–1 week. No preservatives; recommended for single use.

Reconstitution Recommendation: Reconstitute using sterile water for injection containing 0.9% benzyl alcohol. Slowly inject the solvent along the bottle wall, gently rotating or tilting to mix. Vigorous shaking or vortexing is strictly prohibited to avoid peptide aggregation and denaturation.

Concentration Calculation Example: 2 mg PEG-MGF added to 2 mL sterile water yields a final concentration of 1,000 mcg/mL. On the U-100 insulin injector, 20 units (0.20 mL) correspond to a dose of 200 mcg.

 

 

Why Choose Us?

As a source manufacturer of peptides, we are committed to providing high-specification research peptide raw materials to research institutions and biopharmaceutical companies worldwide. Our six core advantages:

🏭 Source Factory, Controllable Costs
We own a GMP-standard production workshop, completing the entire process from solid-phase synthesis to purification and freeze-drying in-house, eliminating intermediaries and ensuring competitive pricing and supply chain transparency.

🔬 Professional Synthesis Equipment, Leading Technology
Equipped with fully automated peptide synthesizers, preparative HPLC systems, and freeze-drying units, we utilize Fmoc solid-phase synthesis technology, enabling single-batch synthesis scales from gram to hundreds of grams, supporting PEGylation modification, sequence customization, and labeling modification.

📦 Stable Supply, Ample Inventory
We have established a standardized raw material reserve system and a multi-batch rolling production mechanism, maintaining regular specifications in stock. We support flexible delivery from small-batch samples to large-volume purchases, with controllable lead times.

🧪 Purity ≥99%, Superior Quality
Each batch of products undergoes dual identification using reversed-phase high-performance liquid chromatography (RP-HPLC) and mass spectrometry (MS) to ensure correct molecular identity and purity exceeding 99%, providing a detailed Certificate of Account (COA).

✅ Stable Quality, Batch-to-Batch Consistency
We strictly adhere to the ISO quality management system, ensuring full traceability from raw amino acids to the final lyophilized powder. Batch-to-batch variation (RSD) is <2%, guaranteeing the reproducibility and reliability of your research data.

🛡️ Guaranteed After-Sales Service and Technical Support
We have a professional peptide technology team providing guidance on reconstitution, storage solutions, and experimental design suggestions. Unconditional returns and exchanges are supported for products with quality issues, ensuring worry-free purchasing.

 

 

FAQ
Q: Where are you located?

A: Our products are from Shenzhen, China.

Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity level can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are all available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Computing) report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM/ODM?

A: OEM/ODM service is supported, subject to minimum order quantity requirements.

Q: What are your after-sales service terms?

A: After the customer receives the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting customer rights.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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