Follicle-Stapressin-344
Description: Follicle-Stapressin-344 is a recombinant human follicle-stapressin containing 344 amino acids. It blocks myostatin and increases muscle mass.
Benefits: These results demonstrate that FS-344, delivered via a single AAV1 injection, enhances muscle volume and strength through its inhibitory effect on myostatin, exhibiting good tolerability and a duration of effect exceeding 2 years.
Function: Originally isolated from porcine ovarian follicular fluid, in vitro studies have revealed its function as an inhibitor of follicle-stimulating hormone (FSH) release.
Disadvantages: Follicle-stapressin blocks the action of various proteins and hormones, such as activators, which are involved in apoptosis, metabolism, endocrine homeostasis, bone growth, fibrosis and inflammation, neurogenesis, endothelial cell tubular formation, and cancer development; and myostatin, which inhibits muscle growth.
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