Vasoactive intestinal peptide (VIP) is an endogenous neuropeptide widely distributed in the human central nervous system and peripheral tissues. In the fitness industry, VIP is primarily used due to its powerful vasodilatory, anti-inflammatory, and metabolic modulatory properties: high-intensity training can lead to local ischemia, inflammation buildup, and decreased insulin sensitivity. VIP relaxes smooth muscle, dilates blood vessels, improves microcirculation, and modulates the immune response by activating adenylate cyclase and increasing intracellular cAMP levels. It is used as a "pump and recovery" strategy to maximize muscle pump during training, accelerate lactic acid clearance, improve nutrient delivery, and help athletes alleviate systemic inflammation caused by overtraining. It belongs to the "vascular function and immune modulator" category.
Original VIP (Vasoactive Intestinal Peptide) 10 mg/bottle
Pure vasodilator peptide powder, circulation and recovery complex, VIP raw material powder, specially formulated for bodybuilding to deliver the ultimate pump.
CAS No.: 23950-41-2
EINECS No.: Not listed (Research Peptide)
Molecular Formula: C139H233N39O38S
Molecular Weight: Approx. 3078.7 Da
Melting Point: >200°C (decomposes; peptides generally do not have a defined melting point).
Appearance: White lyophilized powder
Uses: VIP is a key choice for bodybuilders undergoing high-intensity training, pursuing ultimate pump effects, or attempting to improve microcirculation to break through growth bottlenecks. It is designed to maximize vasodilation and promote nutrient delivery. It is especially suitable for those concerned about vasoconstriction, insufficient pump, or slow post-training recovery. Many competitive bodybuilders incorporate this potent vasodilator into their high-intensity training programs during competition preparation. VIP is generally considered an indispensable "congestion-enhancing" component in such training programs, ensuring adequate perfusion of muscle tissue even under extreme congestion, accelerating the clearance of metabolic waste, and preventing performance decline due to ischemia.
Key Advantages and Characteristics:
First, as a functional peptide, VIP's advantages are mainly reflected in the following aspects:
Firstly, it possesses highly defined biological activity:
VIP has clearly defined receptor targets in vivo, primarily functioning through VPAC1 and VPAC2 receptors. Its signaling pathway is well-defined, and research results are highly reproducible.
Secondly, it possesses multiple physiological regulatory capabilities:
VIP not only participates in vascular smooth muscle relaxation but also plays an important role in immune regulation, inflammatory response suppression, neuroprotection, and intestinal function regulation, making it highly valuable in multidisciplinary research.
Thirdly, as an endogenous peptide, it exhibits good safety:
VIP, as one of the naturally occurring peptides in the human body, has good biocompatibility and systemic tolerability, which is an important reason for its attention in the field of drug development.
Fourth, well-defined structure, easy synthesis and modification: VIP has a clear amino acid sequence, suitable for high-purity preparation using solid-phase peptide synthesis technology, and facilitates structural modification and functional enhancement.
Fifth Part: Stability and Storage Conditions
VIP is highly sensitive to environmental conditions, therefore stability management is crucial. Raw material powder should generally be stored under low-temperature, dry, and light-protected conditions, with a recommended storage temperature of -20°C or lower.
Dissolved VIP solutions should not be stored for long periods. They should be aliquoted and stored at low temperatures, avoiding repeated freeze-thaw cycles. Repeated freeze-thaw cycles accelerate peptide chain breakage and reduce activity, which are common factors affecting VIP stability.
During transportation and long-term storage, vacuum freeze-drying, inert gas protection, and light-protected packaging are important means to ensure VIP quality.
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