Application Scenarios
AOD9604 is primarily used in the following research and clinical scenarios:
1. Weight Management and Body Composition Optimization
AOD9604 targets lipid metabolism at the adipocyte level, rather than acting by suppressing appetite. It promotes lipid oxidation while preserving lean body tissue, thus offering complementary value for patients who have completed a GLP-1 weight loss cycle and entered the maintenance phase of body remodeling. It should be noted that a 24-week phase IIb clinical trial involving 536 participants failed to achieve statistical significance on the primary endpoint of weight loss in obesity, indicating limited evidence for the compound's clinical efficacy.
2. Sports Medicine and Tissue Repair Exploration
Some animal studies have explored the potential of AOD9604 in cartilage regeneration. For example, intra-articular administration in a rabbit osteoarthritis model showed improvement in cartilage-related parameters. However, to date, no publicly published randomized controlled trials in humans support its clinical application in osteoarthritis or tissue repair.
3. Metabolic Health Research
In preclinical models, AOD9604 upregulated the expression level of β3-adrenergic receptors in adipocytes. This receptor is a major lipolysis receptor in adipose tissue, suggesting its potential role in lipid metabolism regulation pathways.
Regulatory Status: AOD9604 is currently not approved by the FDA for any indication. As of 2026, it is restricted as a Category 2 FDA 503A bulk active pharmaceutical ingredient and requires a prescription from a compliant pharmacy. The World Anti-Doping Agency (WADA) lists it as a prohibited substance for competitive use.
Storage and Usage
Storage Conditions
Lyophilized Powder Form: Recommended storage at -20°C, where it maintains stability for over 4 years.
Reconstituted Solution: Recommended aliquoting and freezing; avoid repeated freeze-thaw cycles.
Formulation stability studies show that compatibility with basic amino acids (such as arginine) significantly improves the stability of AOD9604 in solid dosage forms.
Usage
Route of Administration: Subcutaneous injection is commonly used in preclinical studies; oral formulations have also been developed as candidates for anti-obesity drugs.
Dosage Reference: In animal studies, an oral dose of 500 μg/kg/day for 19 days significantly reduced weight gain in obese Zucker rats. Human dosage should be individualized according to a physician's prescription.
Handling Precautions: All peptide products should be handled under aseptic conditions. When reconstituted, it is recommended to use sterile water for injection or physiological saline, gently rotating to dissolve, avoiding vigorous shaking that could cause peptide chain aggregation.
Why Choose Us?
Direct Factory, Vertical Supply
We are the source manufacturer of AOD9604 peptide, employing an optimized solid-phase synthesis process. Starting with Fmoc-Phe-Wang resin, we sequentially couple amino acids, undergoing cleavage, oxidative bridging, reverse-phase preparation, and lyophilization to obtain the finished product. Direct supply from the source means eliminating intermediate steps, providing significant advantages in cost and response speed.
Professional Production Equipment and Process Control
Relying on a professional peptide synthesis production line, we strictly control the key process parameters at every stage. Our patented process achieves peptide purity exceeding 86%, further enhanced by reverse-phase purification, while effectively controlling side reactions.
Stable Supply and Guaranteed Production Capacity: As a manufacturing company, we possess stable and sustainable production capacity, capable of meeting diverse needs from small-scale R&D supply to commercial mass production, eliminating the risk of supply chain disruptions.
High Purity and Quality Stability: We implement a rigorous quality control system. Key indicators such as product purity, impurity profile, and endotoxin levels all meet the quality standards for peptide raw materials, ensuring consistency and reproducibility of each batch.
Comprehensive After-Sales and Technical Support: We not only provide high-quality products but also offer full-process technical support, from usage consultation to formulation development, making us your long-term, reliable partner.
FAQ:
Q: Where are you located?
A: Our products are from Shenzhen, China.
Q: What is the minimum order quantity?
A: The minimum order quantity is 10 bottles/set.
Q: How long does it take to ship?
A: In-stock orders will be shipped within 24 hours.
Q: What purity level can you provide?
A: Standard purity 99%.
Q: Which courier service do you use?
A: FedEx, DHL, UPS, and postal services are all available.
Q: How long does shipping take?
A: Approximately 10-15 days.
Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Computing) report?
A: Yes, all goods undergo professional testing before shipment.
Q: Do you support OEM/ODM?
A: OEM/ODM service is supported, subject to minimum order quantity requirements.
Q: What are your after-sales service terms?
A: After the customer receives the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting customer rights.
Q: What payment methods are available?
A: We support bank transfer, Bitcoin, Transferwise, and Xoom.
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