Application Scenarios (Research Use)
For laboratory in vitro/in vivo research use only. Not suitable for human or clinical treatment.
Endocrine and Metabolic Studies: As a GHRH receptor agonist, CJC-1295 with DAC is widely used to study the biological effects of sustained GH-IGF-1 axis activation. Its long-acting nature allows researchers to simulate a sustained baseline elevation of hormone levels in animal models, rather than the natural pulsatile secretion pattern, thereby exploring the regulatory mechanisms of sustained GH exposure on lipolysis (free fatty acid mobilization), protein synthesis, and energy metabolism.
Pharmacokinetics and Long-Acting Formulation Studies: As a classic example of peptide long-acting modification technology, this raw material is often used to evaluate the effects of albumin binding strategies on peptide half-life, biodistribution, and clearance pathways, serving as an important reference for the development of next-generation long-acting peptide drugs.
Tissue Repair and Body Composition Studies: In preclinical studies, it is used to investigate the potential effects of sustained elevated IGF-1 levels on lean body mass maintenance, lipid metabolism, collagen synthesis, and soft tissue repair such as joints and tendons.
Why Choose Us (Source Factory)
The synthesis of CJC-1295 with DAC presents challenges in achieving the yield of 30 peptide chains, maintaining the integrity of the maleimide group in the DAC, site-specific coupling, and controlling aggregation and free DAC. Batch-to-batch variations directly impact the reproducibility of research data. As a source factory for peptides, we offer:
Direct Supply: We produce and sell directly, eliminating middlemen and markups; we support tiered orders starting from 10 mg–kg, with controllable delivery times and prices.
Professional Equipment: Fmoc-SPPS long-chain synthesis + site-directed Lys-DAC coupling + preparative-grade HPLC purification + MS/amino acid analysis/acetate moisture detection. Each batch includes HPLC ≥98% (customizable ≥99%), MS, and COA.
Stable Quality: Internal control of monomer purity, free DAC, single impurities, endotoxin (research grade optional), and moisture; nitrogen-filled aluminum foil packaging to prevent maleimide hydrolysis and hygroscopic aggregation.
Stable Supply: We maintain a constant inventory of pilot-scale and scale-up processes to prevent discoloration, activity drift, or supply disruptions associated with batch changes in commercially available "repackaged bottles."
Clear Compliance: We clearly label our products as "Research Use Only" and provide support for institutional audits, import cold chain logistics, and reconstitution technology consultation.
Storage and Usage Instructions
1. Storage Conditions
Unopened Lyophilized Powder: Sealed, protected from light and moisture; -20℃ for long-term storage (recommended), 2–8℃ for short-term storage ≤1 month; shelf life 24 months.
Opened: Store in a desiccator/nitrogen-filled container, avoiding repeated exposure to room temperature. It is recommended to aliquot according to usage.
Reconstituted Solution: 2–8℃ for short-term storage (≤7 days); long-term storage requires aliquoting at -20℃ or -80℃; repeated freeze-thaw cycles are strictly prohibited (damages DAC coupling integrity).
Contraindications: Avoid strong acids and alkalis (unstable outside pH 4–8), high temperatures (>30℃ accelerates aggregation), direct sunlight, and vigorous shaking.
2. Reconstitution Recommendations (Research-Grade Lyophilized Powder)
It is recommended to use sterile antibacterial water (BAC, containing 0.9% benzyl alcohol) or sterile PBS/pH 7.4 buffer. Slowly pour the powder along the bottle wall, never directly onto the powder. Gently swirl without shaking; it will dissolve in 1–2 minutes until clear.
For poor solubility, first aid with a small amount of dilute acetic acid (0.1% AcOH) or DMSO (<10%) before diluting to the aqueous phase.
Concentration Calculation: Peptide mass (mg) ÷ Added volume (mL) = Working concentration (mg/mL), e.g., 5 mg + 2 mL = 2.5 mg/mL.
Discard any solution that is cloudy, discolored, or contains particles.
3. Experimental Notes
For in vitro/animal research models only; directly claiming that it can be injected into humans is strictly prohibited.
Coexistence with strong oxidants and free thiol reagents will consume DAC maleimide; the coupling reaction system needs to be evaluated separately.
FAQ
Q: Where are you located?
A: Our products are from Shenzhen, China.
Q: What is the minimum order quantity?
A: The minimum order quantity is 10 bottles/set.
Q: How long does it take to ship?
A: In-stock orders will be shipped within 24 hours.
Q: What purity can you provide?
A: Standard purity 99%.
Q: Which courier service do you use?
A: FedEx, DHL, UPS, and postal services are available.
Q: How long does shipping take?
A: Approximately 10-15 days.
Q: Can you provide a COA (Certificate of Authorization) and HPLC (High-Performance Computing) report?
A: Yes, all goods undergo professional testing before shipment.
Q: Do you support OEM/ODM?
A: OEM/ODM service is supported, subject to minimum order quantity requirements.
Q: How are after-sales services handled?
A: After the customer signs for the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to the service principle of pragmatism and responsibility, actively respond to and properly handle all kinds of issues, without shirking responsibility or avoiding problems, and do our best to protect the rights and interests of our customers.
Q: What payment methods are available?
A: We support bank transfer, Bitcoin, Transferwise, and Xoom.
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