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SS-31 (10 Mg/vial) Cardiovascular And Neuro-protection And Repair (CAS: 736992-21-5)

SS-31 (10 Mg/vial) Cardiovascular And Neuro-protection And Repair (CAS: 736992-21-5)

SS-31 (Elamipretide), also known as MTP-131 or Bendavia, is a mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) with a molecular weight of approximately 639.74. It is distinguished by its ability to selectively accumulate in the inner mitochondrial membrane; by binding to cardiolipin, it stabilizes mitochondrial cristae structure, reduces oxidative stress, and enhances the efficiency of ATP production. Originally developed by the Szeto-Schiller team, SS-31 is currently one of the most extensively studied small-molecule peptides in the field of mitochondria-targeted therapy.

Product Introduction

Application Scenarios
Research on SS-31 spans several fields related to mitochondrial dysfunction:

Cardiovascular protection: In models of ischemic cardiomyopathy, SS-31 has been shown to reduce myocardial infarct size and improve mitochondrial function.

Neuroprotection and repair: In spinal cord injury models, SS-31 promotes the recovery of motor function and reduces neuronal apoptosis by preserving mitochondrial bioenergetics.

Metabolism and age-related muscle function: In aging mouse models, SS-31 reverses the age-related decline in mitochondrial ATP production and improves redox balance.

Central nervous system (CNS) degeneration: SS-31 is utilized in the design of mitochondria-targeted nanosystems for neurodegenerative diseases, such as Alzheimer's disease.

 

 

 

Benefits for Bodybuilding
Research on SS-31 regarding athletic performance and muscle function focuses on the following areas:

Enhanced exercise endurance and fatigue resistance: In aging mouse models, an 8-week treatment regimen of SS-31 (3 mg/kg/day) significantly increased treadmill endurance and improved the fatigue resistance of the gastrocnemius muscle. Another study demonstrated that acute SS-31 treatment restores contraction and relaxation rates in aging muscle and repairs exercise-induced AKT phosphorylation signaling.

Improved mitochondrial energy production: SS-31 reverses the age-related decline in maximal mitochondrial ATP production and enhances the coupling efficiency of oxidative phosphorylation (P/O ratio). This mechanism is directly relevant to muscle activity during high-intensity training that relies on mitochondrial energy supply.

Reduction of oxidative stress: By targeting mitochondria, SS-31 reduces the production of reactive oxygen species (ROS) and reverses S-glutathionylation of protein cysteine ​​residues, thereby improving the muscle redox state.

Preservation of muscle mass: In aging studies, the gastrocnemius muscle mass in the SS-31 treatment group was significantly greater than that of the control group, suggesting a potential inhibitory effect on muscle atrophy.

 

 

 

Storage and Usage
Storage conditions: SS-31 should be stored at -20°C in a sealed container, protected from light. Shipping is typically conducted under low-temperature conditions using ice packs.

Solubility: SS-31 is water-soluble. It is recommended to select an appropriate solvent based on experimental requirements to prepare the stock solution. Once prepared, the solution should be aliquoted and stored properly; avoid repeated freeze-thaw cycles to prevent product degradation.

Precautions: Avoid inhalation or contact with skin, eyes, and clothing; the material may be mildly irritating. Please refer to relevant literature or your research design for specific usage protocols (dosage, route of administration).

 

 

 

Why Choose Us?
We understand that quality and stability are the cornerstones of partnership in the peptide industry. As a direct manufacturer, we offer the following guarantees:
Professional Equipment and Direct Manufacturing: We operate our own production facilities equipped with professional peptide synthesis machinery. We oversee the entire production process-from raw material synthesis to purification-ensuring full traceability for every batch.
High Purity and Consistent Quality: We employ advanced synthesis and purification techniques (such as HPLC) to ensure a product purity exceeding 98%. Our products demonstrate high batch-to-batch consistency, meeting the rigorous standards required for scientific research and applications.
Reliable Supply and Worry-Free After-Sales Service: Backed by a mature production management system and robust manufacturing capacity, we ensure a stable supply. We also provide comprehensive technical support and after-sales service to address any questions you may have during use.
Choosing us means choosing professionalism, rigor, and peace of mind. We look forward to becoming your trusted partner.

 

 

 

FAQ
Q: Where are your products manufactured?
A: Our products are manufactured in Shenzhen, China.
Q: What is the Minimum Order Quantity (MOQ)?
A: The MOQ is 10 vials/sets.
Q: How quickly do you ship orders?
A: Orders for in-stock items are shipped within 24 hours.
Q: What purity levels do you offer?
A: The standard purity is 99%.
Q: Which shipping carriers do you use?
A: We use FedEx, DHL, UPS, and postal services.
Q: How long does shipping take?
A: Approximately 10–15 days.
Q: Can you provide COA and HPLC test reports?
A: Yes, we can; all products undergo professional testing before shipment.
Q: Do you offer OEM services?
A: Yes, we offer OEM services, subject to minimum order quantity (MOQ) requirements.
Q: How do you handle after-sales issues?
A: If a customer confirms a quality issue caused by our manufacturing after receiving the goods, we will provide a free replacement or a refund. We are committed to a pragmatic and responsible service philosophy, proactively resolving any issues without making excuses or shirking responsibility, and we always prioritize our customers' interests.
Q: What payment methods do you accept?
A: We accept bank transfers, Bitcoin, TransferWise, and Xoom.

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