AOD9604 Raw Material Product Introduction
AOD9604 (full name: Anti-Obesity Drug 9604, CAS: 221231-10-3) is a synthetic long-acting peptide raw material derived from the C-terminal 176-191 amino acid fragment of human growth hormone (HGH), specifically developed for research fields such as fat loss, metabolic regulation, and cartilage repair.
Basic Raw Material Information
| Chinese Name | AOD9604 (Anti-obesity peptide 9604) |
| English Name | AOD-9604 / HGH Frag 176-191 |
| CAS Number | 221231-10-3 |
| Molecular Weight | 1815.1 Da |
| Appearance | White to off-white lyophilized powder |
| Purity Standard | ≥98.0% (HPLC), single impurities ≤2.0% |
| Raw Material Source | Solid-phase peptide synthesis (SPPS), fully chemical synthesis, not natural extraction |
Molecular Structure and Core Characteristics
- Amino Acid Sequence (16... Peptide)
- Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
- (Abbreviation: YLRIVQCRSVEGSCGF)
- Key Structural Modifications
- N-terminal tyrosine (Tyr): Enhances peptide chain stability and resists enzymatic degradation
- Cysteines at positions 7 and 14 (Cys): Form intramolecular disulfide bonds, stabilizing the cyclic conformation
Core Mechanism of Action
Precisely mimics the lipolysis region of HGH, retaining only fat-reducing activity while eliminating side effects such as growth promotion and blood glucose interference
Physicochemical Properties (Raw Material Grade)
- Solubility: Easily soluble in water, physiological saline, and DMSO (10mg/mL+)
- Stability
- Lyophilized powder: Stable for 2 years when stored in a sealed container protected from light at -20℃
- After reconstitution: Refrigerate at 2-8℃ and use within 30 days
- Storage Conditions: Dry, low temperature, sealed, avoid repeated freeze-thaw cycles
- Density: 1.5±0.1 g/cm³ Refractive Index: 1.667 IV. Core Advantages of Raw Materials Specifically targets fat reduction with no side effects Acts only on fat cells, promoting lipolysis and inhibiting lipid production without affecting blood sugar, insulin, or growth function High activity and high purity Research-grade purity ≥99%, low endotoxin (<1 EU/mg), few impurities, and high safety Strong stability Disulfide bonds and N-terminal modification enhance resistance to enzymatic degradation, with a half-life of approximately 24-36 hours in vivo Multi-effect research value Combines multiple activities including fat reduction, cartilage repair, bone density enhancement, and metabolic regulation V. Main Uses of Raw Materials (Research/ (Industrial)
- Obesity and Metabolic Research: Abdominal fat, visceral fat, and body fat percentage regulation mechanisms
- Muscle and Body Composition: Promotes fat breakdown, retains lean body mass, and increases muscle mass ratio
- Bone and Joint Repair: Stimulates chondrocyte proliferation and collagen synthesis, improving osteoarthritis
- Anti-aging Research: Skin elasticity, metabolic rejuvenation, and cell repair
- Drug Development: Candidate peptide raw materials for anti-obesity, metabolic syndrome, and osteoarthritis
Quality Specifications (Standard Raw Material)
| Appearance | White to off-white lyophilized powder |
| Purity (HPLC) | ≥98.0% |
| Impurities | ≤2.0% |
| Moisture | ≤8.0% |
| Acetate | 4.0%-10.0% |
| Endotoxin | <1 EU/mg (injection grade) |
| Packaging | 1mg/5mg/10mg/1g lyophilized powder vial |
Safety and Compliance Notice

For research/industrial use only. Not for medical, food, or human injection.
Handling requires professional personnel, a suitable laboratory environment, and protective equipment.
Subject to **WADA (World Anti-Doping Agency)** Listed as a banned substance, its use by athletes is strictly prohibited.
Summary: AOD9604 is a high-purity, high-activity, and high-safety HGH-derived fat-reducing peptide raw material. It is prepared by solid-phase chemical synthesis, and its structure is optimized through disulfide bond cyclization and N-terminal modification. It has core advantages such as specific fat reduction, stable and long-lasting effects, and multi-effect research, making it a high-quality research raw material in the fields of obesity, metabolism, muscle repair, and bone and joint diseases.
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