High-purity Peptide Raw Materials CJC1295 with DAC

CJC1295 with DAC (full name: CJC-1295 Drug Affinity Complex, CAS No.: 446262-90-4) is a long-acting synthetic peptide raw material, with a growth hormone-releasing hormone (GHRH) analogue as its core component. It is prepared through chemical synthesis and is used in scientific research, biological experiments, and related R&D fields.

Polypeptide backbone (CJC1295 core)

• Sequence Composition: 29 amino acids, based on human GHRH fragments 1-29
• Key Modification: L-alanine at position 2 → D-alanine, enhancing resistance to enzymatic hydrolysis (DPP-4) stability
• Function: Binds to pituitary GHRH receptors, promoting growth hormone (GH) secretion

DAC Key Functional Group (Long-Lasting Effect)

• Full Name: Drug Affinity Complex
• Structure: Maleimidopropionic acid, linked to the N-terminus of the peptide chain via a lysine residue.
• Function: Covalently binds to plasma albumin, extending the half-life from 7-8 minutes to 6-8 days.

• Solubility: Easily soluble in water, physiological saline, and DMSO, suitable for formulation into injectable solutions.
• Stability
• Lyophilized Powder: Stable for 2 years when stored at -20℃ in a light-protected, sealed container.
• After Reconstitution: Refrigerate at 2-8℃ and use within 30 days.
• Storage Conditions: Dry, sealed, and at low temperature (-20℃), avoid repeated freeze-thaw cycles.

• Long-Lasting and Sustained Release: DAC modification enables 1-2 doses per week, continuously enhancing GH and IGF-1.
• High Purity: Industrial grade ≥98%, research grade ≥99%, low impurities, low endotoxins.
• Stable Activity: Anti-enzymatic and antioxidant, with sustained-release effects in vivo.
• Specific Action: Specifically promotes GH. Secretion does not affect prolactin, high safety.

• Growth Hormone Related Research: GH secretion regulation, anti-aging, metabolic regulation
• Muscle and Body Composition Research: Promotes protein synthesis, muscle gain, fat loss
• Repair and Anti-aging: Cell repair, collagen synthesis, bone density improvement, immune enhancement
• Drug Development: Long-acting peptide drugs, candidate raw materials for growth hormone deficiency and metabolic syndrome

For research/industrial use only, not for medical, food, or human injection.

Operation requires professional personnel, a suitable laboratory environment, and protective equipment.

Regulations for peptide raw materials vary by country; local regulations must be followed.

Summary CJC1295 with DAC is a high-purity, long-acting GHRH peptide raw material, prepared by chemical synthesis. Its core is a 29-amino acid backbone + DAC long-acting group. It has the advantages of long half-life, high purity, stable activity and clear function. It is widely used in scientific research and drug development scenarios such as growth hormone, metabolism, muscle repair, and anti-aging. It is a high-quality raw material in the field of peptides.

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