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Kisspeptin (10 Mg/vial) For Regulating Ovulation And Promoting Oocyte Maturation (CAS: 374675-21-5)

Kisspeptin (10 Mg/vial) For Regulating Ovulation And Promoting Oocyte Maturation (CAS: 374675-21-5)

Kisspeptin is a peptidergic neurohormone encoded by the *KISS1* gene; it was initially discovered for its ability to suppress metastasis in melanoma and breast cancer and was originally named "metastin." Subsequent research has revealed that kisspeptin plays a pivotal role in regulating the hypothalamic-pituitary-gonadal axis by activating its receptor, GPR54 (also known as KISS1R).

Product Introduction

Clinical Applications

Kisspeptin holds broad prospects for clinical application across several fields:

Reproductive Medicine: Kisspeptin can be used to regulate ovulation and promote oocyte maturation, making it particularly suitable for women at high risk of ovarian hyperstimulation syndrome. Additionally, it serves as a tool for assessing GnRH neuronal function and acts as a key regulator in the onset of puberty.

Treatment of Reproductive Disorders: Research indicates that Kisspeptin has potential therapeutic value for reproductive disorders such as hypothalamic amenorrhea and polycystic ovary syndrome (PCOS). Its analogs, such as TAK-448, have demonstrated potent agonist activity in both healthy women and patients with hypothalamic amenorrhea.

Novel Non-invasive Administration: A study published in 2025 demonstrated that intranasal administration of Kisspeptin-54 rapidly stimulates gonadotropin release in healthy men and women, as well as in patients with hypothalamic amenorrhea, without causing side effects or adverse events. This offers the first non-invasive method for the clinical management of reproductive disorders.

 


Benefits in Bodybuilding
Kisspeptin demonstrates unique value in the field of bodybuilding, primarily in the following areas:

Restoring Endogenous Testosterone Secretion: Bodybuilders using anabolic steroids often experience reduced luteinizing hormone (LH) pulse frequency and secretion due to the suppression of GnRH expression. Kisspeptin stimulates GnRH secretion, thereby restoring pulsatile LH secretion and aiding the recovery of natural testosterone production following a steroid cycle.

Alleviating Exercise-Induced Hypogonadism: Overtraining and insufficient caloric intake can lead to reduced LH pulse frequency and secretion in athletes (particularly female athletes). Kisspeptin administration has been shown to sustain a twofold increase in LH secretion even in the presence of elevated androgens, offering a novel therapeutic mechanism to correct both exercise-induced and steroid-induced hypogonadism.

Supporting Endocrine Health in Female Athletes: For female athletes, Kisspeptin may help support estradiol rhythms and physiological recovery.

 

 

Storage and Usage Instructions
Proper storage and usage are crucial for maintaining the activity of Kisspeptin:

Storage of Lyophilized Powder: The lyophilized powder should be stored at -20°C, where it remains stable for at least 4 years; for maximum long-term stability, storage at -80°C is recommended. Store in a desiccator and protect from light.

Storage After Reconstitution: The reconstituted aqueous solution can be stored at -20°C for up to 3 months and at -80°C for up to 6 months. Aliquot the solution to avoid repeated freeze-thaw cycles.

Reconstitution Method: Before reconstitution, briefly centrifuge the vial to settle the powder at the bottom and allow it to reach room temperature before opening to prevent condensation. Dissolve using sterile water or high-purity DMSO, and gently vortex until completely dissolved. After aliquoting, rapid freezing is recommended; flash freezing in liquid nitrogen is superior to slow freezing.

Stability Data: Accelerated thermal degradation tests show no significant degradation or precipitation after incubation at 37°C for 48 hours; the loss rate remains below 5% within the shelf life under proper storage conditions.

 

 

Why Choose Us
As a primary manufacturer of Kisspeptin, we offer the following core advantages:

Direct Supply from the Source: We operate our own production lines and a comprehensive supply chain system. We control the entire process-from raw material procurement to the release of finished products-ensuring traceability and guaranteed quality right from the source.

Professional Production Equipment: We are equipped with modern production facilities and a team of professional engineers and technicians. We utilize advanced peptide synthesis and purification processes to ensure high product purity and batch-to-batch consistency.

Stable Supply: Our large-scale production capacity enables us to meet demands for large orders and long-term supply schedules, providing customers with a consistent and reliable source of raw materials.

Purity and Quality Assurance: Our product purity leads the industry. Each batch undergoes rigorous quality testing to ensure compliance with international standards.

Worry-Free After-Sales Service: We provide comprehensive technical support and after-sales services to resolve any issues encountered during use, ensuring a worry-free partnership.

 

 

 

FAQ
Q: Where are your products manufactured?

A: Our products originate from Shenzhen, China.
Q: What is the minimum order quantity (MOQ)?
A: The MOQ is 10 bottles/sets.
Q: How soon do you ship?
A: Orders for in-stock items are shipped within 24 hours.
Q: What purity levels do you offer?
A: The standard purity is 99%.
Q: Which shipping carriers do you use?
A: Options include FedEx, DHL, UPS, and postal services.
Q: How long does shipping take?
A: Approximately 10–15 days.
Q: Can you provide COA and HPLC test reports?
A: Yes; all products undergo professional testing before shipment.
Q: Do you offer OEM services?
A: Yes, OEM services are available, subject to MOQ requirements.
Q: How do you handle after-sales issues?
A: If a quality issue caused by our production is confirmed after the customer receives the goods, we offer free replacements or refunds. We are committed to a pragmatic and responsible service approach, actively addressing and resolving issues without evasion or excuses, while fully protecting our customers' interests.
Q: What payment methods do you accept?
A: We accept bank transfers, Bitcoin, TransferWise, and Xoom.

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