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IGF-DES 2mg/vial Powerfully Promotes Muscle Growth And Repair.

IGF-DES 2mg/vial Powerfully Promotes Muscle Growth And Repair.

IGF-DES is a C-terminal truncated polypeptide of insulin-like growth factor-1 (IGF-1) synthesized through genetic engineering. By removing the key binding site for the carrier protein (IGFBP-3), this fragment cannot bind to the carrier protein in the blood, thus achieving extremely high receptor affinity in its free state. Its biological activity is approximately 10 times that of ordinary IGF-1, but its most significant characteristic is its extremely short half-life (only 20-30 minutes), exhibiting a "burst" localized mode of action and being less likely to induce systemic metabolic side effects.

Product Introduction

Applicable Methods

1. Route of Administration: Local subcutaneous or intramuscular injection into the target tissue is commonly used in scientific research experiments, directly injecting into the target site; intravenous administration is not recommended. Injection sites need to be rotated to prevent local irritation and inflammatory reactions; repeated injections at the same site are strictly prohibited.

2. Dosage and Dosing Cycle (Research Reference)

- Single Dosage: 20-100 μg/site, commonly ranging from 20-50 μg; adjust the dose gradient according to cell, animal models, or experimental goals. Due to its high potency, it is advisable to start with a low dose.

- Timing of Administration: Administration is usually given immediately after model establishment or injury treatment; in animal and in vitro studies, single daily administration is recommended, and multiple daily injections are not advised.

- Cycle Regimen: A common regimen is 4 weeks of dosing, followed by a 2-4 week interval for observation to avoid receptor desensitization and potential proliferation risks; there is no unified human clinical dosing regimen.

3. Reconstitution and Handling Tips: Reconstitute the lyophilized powder with sterile antibacterial water to prepare a clear, colorless solution; the peptide has a very short half-life, and should be used in experiments as soon as possible after reconstitution. There are no standard dosing guidelines for missed doses. If dosing is interrupted, the experimental protocol should be restarted; dosing dosing in double doses is prohibited.

 

Main Application Scenarios

Cell Culture and Signal Processing: As an IGFBP-independent IGF-1R agonist, it is used to study the PI3K/Akt/mTOR, RAS/MAPK pathways, satellite cell activation, and protein synthesis.

Muscle Regeneration and Local Anabolism (Preclinical): Observing local muscle hypertrophy, muscle satellite cell proliferation, and post-exercise repair in animal models.

Tissue Repair and Metabolic Research: Intestinal mucosal repair, nerve damage protection (endogenous brain fragments), GH/IGF axis regulation models.

Sports Science/Doping Monitoring: Due to its strong anabolic potential, it is listed as a prohibited peptide and is used in anti-doping detection research.

 

Storage Conditions:

As a temperature-sensitive peptide, IGF-DES must strictly adhere to the following cold chain storage guidelines: Unreconstituted (lyophilized powder): It is recommended to store at -20°C or lower, protected from light and sealed. It can typically be stored stably for 1 to 2 years. After reconstitution (solution state): Extremely prone to degradation or aggregation. Must be immediately aliquoted into small volumes and stored at -20°C or -80°C. If refrigerated at 4°C, must be used within several days (usually 2-3 days), and repeated freeze-thaw cycles must be strictly avoided.

 

FAQ
Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Liquid Chromatography) test report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM labeling? A: OEM branding service is supported, subject to minimum order quantity requirements.

Q: How is after-sales service handled?

A: After the customer receives the goods, if a quality issue is confirmed to be caused by our production, they can enjoy free replacement or a refund. We uphold a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting the rights and interests of our customers.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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