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Cardiogen 20mg/vial in Studies Of Myocardial Injury Repair And Cardiac Remodeling

Cardiogen 20mg/vial in Studies Of Myocardial Injury Repair And Cardiac Remodeling

Cardiogen (cardiac regulatory peptide) is a linear tetrapeptide (sequence: Ala-Glu-Asp-Arg, abbreviated as AEDR) composed of alanine (Ala), glutamic acid (Glu), aspartic acid (Asp), and arginine (Arg), belonging to the classic short peptide bioregulators. With a molecular weight of only 489.48 g/mol, it can easily penetrate the cell membrane and enter the cell nucleus. Studies have shown that Cardiogen can specifically target cardiomyocytes and fibroblasts, regulating the transcription of cardiovascular-related genes through epigenetic mechanisms. It not only downregulates the p53 apoptosis pathway and inhibits programmed cell death in cardiomyocytes, but also regulates fibroblast activity and inhibits pathological myocardial fibrosis, thus playing a crucial role in maintaining myocardial structural integrity, improving energy metabolism, and promoting cardiac tissue repair.

Product Introduction

Main Application Scenarios

Cardiogen peptides have extremely high research value in basic cardiovascular medicine, tissue regeneration, and anti-aging research, and are mainly applied in the following areas:

Cardiovascular Disease Mechanism Research: As a core tool molecule, it is used to explore the pathological mechanisms and intervention targets of myocardial ischemia-reperfusion injury, heart failure, and myocardial fibrosis.

Myocardial Repair and Remodeling Models: Used to evaluate its biological effects in promoting myocardial progenitor cell proliferation, improving myocardial contractile function, and balancing the synthesis and degradation of extracellular matrix components (such as collagen).

Apoptosis and Stress Pathway Analysis: Used to study oxidative stress-induced cardiomyocyte damage and the protective role of peptides in protecting the cytoskeleton and maintaining genome integrity.

Aging Heart and Metabolic Research: Used to explore the application of short peptide bioregulators in reversing age-related myocardial function decline, improving mitochondrial ATP production efficiency, and enhancing cardiac stress resistance.

 

 

Why Choose Us?
Source Factory · Professional Equipment · Stable Supply · Consistent Quality

1. Direct Supply from Source Factory

Independent solid-phase synthesis (Fmoc-SPPS) → preparative HPLC purification → freeze-drying → packaging – a closed-loop process, eliminating middlemen and markups. Flexible cooperation is supported for research-grade, API-grade, and customized sequences.

2. Professional Production Equipment

Industrial-grade fully automated peptide synthesizer, Prep-HPLC, analytical HPLC, ESI/MS, and Karl Fischer moisture determination platform; batch traceability, supporting scale-up from 10 mg to kg.

3. Stable Supply

Standardized production lines + safety stock mechanism. Fast delivery for standard specifications (10 mg/100 mg/1 g/customized aluminum foil bags). Large orders can have production schedules locked in, reducing the risk of supply disruptions.

4. Stable Quality

Each batch comes with a complete Certificate of Account (COA):

RP-HPLC purity (research grade ≥98%, customizable ≥99%)

MS molecular weight confirmation (489.5 Da)

Amino acid analysis / sequence consistency

Moisture, acetate, and residual solvent detection

Consistent CQA across batches ensures experimental reproducibility and formulation stability

 

 

Handling Precautions

Reconstitution Method: Slowly add sterile water/sterile water for injection/PBS (pH 6–7) along the bottle wall, gently shake to dissolve; do not vortex or shake violently; for cell experiments, 0.22 μm sterile filtration is required.

Dispensing Practices: Dispense according to single-use dosage to avoid peptide degradation, aggregation, or decreased activity due to repeated freeze-thaw cycles.

Contamination Control: Wear gloves, use sterile and pyrogen-free consumables, and store in the original packaging away from light.

Solubility: AEDR is a hydrophilic short peptide, with good solubility in aqueous solutions and weak acid buffers.

Compliance Notice: This product is for Research Use Only/Industrial Raw Material, not for human use or as a health food. Personnel handling this product should follow laboratory chemical safety guidelines.

 

 

FAQ
Q: Where is your product manufactured?

A: Our products are from Shenzhen, China.

Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity level can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: We offer FedEx, DHL, UPS, and postal services.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Copyright Account) report and HPLC (High-Performance Liquid Chromatography) report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM/ODM?

A: We support OEM/ODM services, subject to minimum order quantity requirements.

Q: How are after-sales services handled?

A: After the customer signs for the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to the service principle of pragmatism and responsibility, actively respond to and properly handle all kinds of issues, without shirking responsibility or avoiding problems, and do our best to protect the rights and interests of our customers.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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