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Testagen Reproductive Endocrinology Pituitary-Thyroid-Gonadal Axis Crossover Study CAS: 1026993-38-3

Testagen Reproductive Endocrinology Pituitary-Thyroid-Gonadal Axis Crossover Study CAS: 1026993-38-3

Testagen is a synthetic tetrapeptide composed of lysine (Lys), glutamic acid (Glu), aspartic acid (Asp), and glycine (Gly). Its most notable characteristic is its nuclear penetration ability—studies have shown that fluorescently labeled Testagen can enter the cytoplasm, nucleus, and even nucleolus of HeLa cells, suggesting a molecular basis for its direct interaction with chromatin and DNA. This intranuclear localization ability gives it unique research value, distinguishing it from traditional receptor-mediated signal peptides.

Product Introduction

Core Application Scenarios

Reproductive Endocrinology and Andrology Research: Testicular aging, Leydig/Sertoli cell function, endogenous testosterone synthesis (StAR/CYP11A1/CYP17A1), spermatogenesis and HPG axis regulation models;

Epigenetics and Short Peptide-DNA Interactions: Chromatin desuppression, histone interactions, promoter region binding, tissue-specific gene reprogramming research;

Pituitary-thyroid-gonadal axis crossover research: Age-related endocrine decline, stress-induced reproductive/thyroid function downregulation animal models;

Peptide Drugs and Delivery Basis: Short peptide nuclear translocation, zwitterionic peptide physicochemical properties, evaluation of bioregulatory peptide candidate lead compounds;

Anti-aging and Tissue Repair Exploration: Oxidative stress downregulation, chronic inflammation suppression, reproductive/endocrine tissue rejuvenation mechanisms research.

Note: This product is a research/industrial grade raw material (RUO), not a registered drug, not food, not cosmetic, and is prohibited for human or animal ingestion.

 

 

Why Choose Our Testagen Peptide?

As a peptide source manufacturer, we provide end-to-end controllable assurance from synthesis and purification to packaging:

Direct supply from the source, eliminating intermediate steps: In-house Fmoc-SPPS solid-phase synthesis + preparative-grade RP-HPLC purification + ESI-MS/AAA identification, with each batch accompanied by COA/MSDS;

Professional production equipment: GMP standard workshop, automated synthesis and freeze-drying lines, clean packaging environment, supporting flexible production capacity at the mg–g–kg level;

Stable quality: HPLC purity ≥98% (customizable ≥99%), accurate sequence, controlled moisture/acetate/endotoxin levels, and traceable batch-to-batch consistency;

Stable supply: We maintain a stock of 10 mg/20 mg/100 mg/1 g aluminum foil vacuum-packed containers, with controllable delivery times, suitable for long-term projects, institutional procurement, and pilot-scale amplification.

 

 

Storage and Handling Guidelines

Unreconstituted (lyophilized powder):

Long-term storage: -20℃ or below (recommended -80℃), sealed, protected from light and moisture, with desiccant; shelf life up to 24 months;

Short-term storage (≤6 months): 2–8℃, protected from light and sealed is also acceptable;

Before reconstitution: Warm to room temperature for 20–30 min before opening to prevent condensation adsorption;

Reconstitution procedure: Slowly add sterile water / 0.9% NaCl / antibacterial water (BAC water) along the bottle wall, do not pour directly onto the lyophilized cake, do not vortex; gently shake to aid dissolution, a clear, colorless solution is normal; KEDG has good water solubility and generally does not require organic solubilizers;

Storage after reconstitution: Refrigerate at 2–8℃, recommended to use within 14–28 days; for long-term storage, please aliquot and freeze at -20℃~-80℃, repeated freeze-thaw cycles are strictly prohibited; use low-absorption tubes, 0.22 μm filtration sterilization;

Operating Requirements: Wear gloves/goggles/laboratory clothing, and handle according to the institution's biosafety and chemical hygiene procedures; dispose of waste in compliance with regulations.

 

 

FAQ
Q: Where are your products manufactured?

A: Our products are from Shenzhen, China.

Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Liquid Chromatography) test report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM labeling?

A: OEM branding service is supported, subject to minimum order quantity requirements.

Q: How is after-sales service handled?

A: After the customer receives the goods, if a quality issue is confirmed to be caused by our production, they can enjoy free replacement or a refund. We uphold a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting the rights and interests of our customers.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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