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5-amino-1 Mq5 Mg/vial Is Used To Regulate Energy And Inhibit Fat. CAS: 42464-96-0

5-amino-1 Mq5 Mg/vial Is Used To Regulate Energy And Inhibit Fat. CAS: 42464-96-0

5-Amino-1MQ (5-amino-1-methylquinolinium; CAS: 42464-96-0) is a small-molecule, selective inhibitor of nicotinamide N-methyltransferase (NNMT). Its primary mechanism of action involves inhibiting NNMT activity to increase intracellular NAD⁺ levels and SAM concentrations, thereby activating signaling pathways associated with metabolic regulation, fatty acid oxidation, and cellular energy homeostasis. Existing research data, derived primarily from preclinical models, indicate its potential value in metabolic regulation and the optimization of body composition.

Product Introduction

Application Scenarios
5-Amino-1MQ is currently primarily used in the following research contexts:

Metabolism and body composition research. In animal models of diet-induced obesity, the compound is used to study its inhibitory effects on fat accumulation and its role in regulating energy expenditure.

Sports nutrition and physical performance research. Due to its regulatory effect on the NAD⁺ metabolic pathway, it is included in research frameworks concerning training adaptation, recovery efficiency, and nutrient partitioning.

Muscle biology research. Studies indicate that it promotes myoblast differentiation *in vitro* and enhances the fusion and regenerative capacity of muscle stem cells in aged mouse models.

Cellular energy metabolism research. As a tool compound for NNMT inhibition, it is used to explore the molecular mechanisms linking the NAD⁺ pathway to the regulation of cellular metabolism.

 

 

Benefits in Bodybuilding
In the context of bodybuilding and physical training, research into 5-Amino-1MQ focuses on the following areas:

Support for fat oxidation. By inhibiting NNMT, the compound promotes a metabolic shift toward oxidative energy production in adipose tissue, potentially helping to optimize body fat levels during fat-loss or body-recomposition phases.

Training energy and endurance. Elevated NAD⁺ levels are closely linked to mitochondrial function and ATP regeneration efficiency; theoretically, this supports energy output and endurance maintenance during high-intensity training.

Nutrient partitioning and insulin sensitivity. NNMT inhibition helps improve glucose metabolism and nutrient partitioning efficiency, favoring the uptake of carbohydrates by muscle tissue over storage as fat.

Recovery and metabolic health. By improving cellular energy status and the metabolic environment, it may indirectly support the recovery process following high-intensity training.

Important Note: All efficacy data currently derive from preclinical studies; clinical evidence in humans has not yet been established.

 

 

Storage and Usage
Storage conditions. Lyophilized powder should be stored at -20°C in a sealed container, protected from light and moisture. Long-term storage is recommended under frozen conditions. Stability is limited after reconstitution; the product should be used promptly. Avoid prolonged exposure to high heat, high humidity, or light.

Usage. In preclinical research, the compound has been administered orally (in animal models). Subcutaneous injection has also been used in research settings. Standard dosages for human use have not been established; any use should be conducted under the guidance of qualified professionals. This product is for research use only and is not intended for human use.

 


Why Choose Us
As a primary manufacturer deeply rooted in the raw material supply chain, we understand that stability and compliance are the cornerstones of long-term trust in the complex international market. We not only supply high-purity raw materials but are also committed to providing a worry-free, seamless purchasing experience:
Primary Manufacturer with Professional Equipment: Leveraging professional production equipment and mature synthesis processes, we control product quality at the source, ensuring the reliability of every batch.
High Purity and Consistent Quality: We strictly implement quality control procedures; our products feature high purity and minimal batch-to-batch variation, guaranteeing consistent quality for your subsequent R&D or production.
Stable Supply and Worry-Free After-Sales Service: With ample production capacity and a robust supply chain system, we ensure timely and stable delivery. We also provide professional, reliable after-sales support, responding promptly to your needs.

 


FAQ
Q: Where are your products manufactured?
A: Our products originate from Shenzhen, China.
Q: What is the minimum order quantity (MOQ)?
A: The minimum order quantity is 10 bottles/sets.
Q: How soon do you ship?
A: Orders for in-stock items are shipped within 24 hours.
Q: What purity levels do you offer?
A: The standard purity is 99%.
Q: Which shipping carriers do you use?
A: Options include FedEx, DHL, UPS, and postal services.
Q: How long does shipping take?
A: Approximately 10–15 days.
Q: Can you provide COA (Certificate of Analysis) and HPLC (High-Performance Liquid Chromatography) reports?
A: Yes, these are available; all goods undergo professional testing before shipment.
Q: Do you offer OEM/private label services?
A: Yes, OEM services are available, subject to minimum order quantity requirements.
Q: How is after-sales service handled?
A: If a quality issue caused by our production is confirmed after the customer receives the goods, we offer free replacement or a refund. We uphold a pragmatic and responsible service philosophy, actively addressing and properly resolving any issues without evasion or excuses, fully safeguarding our customers' interests.
Q: What payment methods do you accept?
A: We accept bank transfers, Bitcoin, TransferWise, and Xoom.

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