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Mazdutide 5mg/vial Effectively Reduces Excess Fat. CAS: 2259884-03-0

Mazdutide 5mg/vial Effectively Reduces Excess Fat. CAS: 2259884-03-0

Mazdutide (development code IBI362) is a novel, fatty acid-modified dual agonist of glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR). This drug is administered subcutaneously once weekly for the treatment of type 2 diabetes and obesity.

Product Introduction

Method of Application

Route: Subcutaneous injection only (abdomen preferred, thigh/upper arm can be alternated); intravenous/intramuscular injection is strictly prohibited.

Frequency: Once a week, at any time, unaffected by food intake; changes in date require an interval of ≥5 days (>120 hours) between doses.

Dose Titration (Standard Regimen):

Weeks 1–4: 2 mg/week (starting)

Weeks 5–8: 4 mg/week

From Week 9 onwards: Maintenance 4 mg or 6 mg/week (6 mg is the upper limit recommended in China; if intolerable, reduce to 4 mg)

Missed Dosage: ≤2 days: administer the original regimen; 2–7 days: administer and rearrange the cycle; 7–21 days: reduce to the previous dose and re-titer; >21 days: return to 2 mg and restart.

Special Populations: Mild to moderate hepatic/renal impairment requires no dose adjustment; contraindicated in pregnancy, lactation, MTC/MEN2, end-stage renal disease, and severe hepatic impairment.

 

Application Scenarios

Long-term weight management in adults

BMI ≥ 28 kg/m² (obese); or BMI ≥ 24 kg/m² with ≥ 1 weight-related comorbidity (hyperglycemia, hypertension, dyslipidemia, fatty liver, OSA, etc.).

Glycemic control in adults with type 2 diabetes

Monotherapy or combination with oral hypoglycemic agents/insulin (hypoglycemia should be monitored when using insulin/sulfonylureas, and dosage should be reduced); especially suitable for those with overweight/obesity, fatty liver, and cardiovascular metabolic risks.

Comprehensive metabolic benefit scenarios

Improves waist circumference, triglycerides, LDL-C, uric acid, liver enzymes, liver fat, and blood pressure; used as an adjunct management for metabolically related fatty liver disease (MASLD), hyperuricemia, etc.

 

 

**Storage Conditions**
Although specific storage temperatures should be based on the drug's instructions, due to the chemical characteristics of these polypeptide biological agents, the following principles are generally recommended:

- **Refrigerated storage**: Unopened drugs are generally recommended to be stored in the refrigerator at 2°C-8°C. Do not freeze. - **Protect from light and moisture:** This medication is sensitive to light and should be kept in its original aluminum foil or cardboard box, avoiding direct sunlight.

- **Storage time at room temperature:** If it needs to be taken out or stored at room temperature, there are usually strict time limits (e.g., no more than a few weeks below 30°C), and it should be kept away from high-temperature areas such as car glove boxes and windowsills to prevent protein denaturation and inactivation.

 

 

FAQ
Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity levels can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Copyright Account) report and HPLC (High-Performance Computing) report? A: Yes, we can provide this service. All goods undergo professional testing before shipment.

Q: Do you support OEM labeling?

A: Yes, we support OEM labeling, but a minimum order quantity must be met.

Q: How is after-sales service handled?

A: After the customer signs for the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to a pragmatic and responsible service principle, actively respond to and properly handle all kinds of issues, without shirking responsibility or avoiding problems, and do our best to protect the rights and interests of our customers.

Q: What payment methods are available?

A: We support bank transfer, Bitcoin, Transferwise, and Xoom.

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