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EPO (branded) 3000 IU/vial Effectively Promotes Erythrocyte Production And Improves Anemia.

EPO (branded) 3000 IU/vial Effectively Promotes Erythrocyte Production And Improves Anemia.

EPO (Erythropoietin) is a glycoprotein hormone composed of 165 amino acids with a molecular weight of approximately 30.4 kDa. The EPO (branded) we provide is a high-purity recombinant protein, typically produced using a Chinese hamster ovary (CHO) cell expression system to ensure it possesses an amino acid sequence and key glycosylation modifications highly consistent with natural human EPO. As a core regulator of erythropoiesis, EPO exerts its anti-apoptotic, cell proliferation- and differentiation-promoting effects by binding to the EPO receptor (EPOR) on the surface of bone marrow erythroid progenitor cells, thereby accelerating reticulocyte maturation and increasing hemoglobin synthesis.

Product Introduction

Main Application Scenarios

Chronic Kidney Disease (CKD) Related Anemia: As a representative erythropoiesis-stimulating agent (ESA), EPO is a first-line option for anemia management in CKD patients. Clinical guidelines recommend individualized dosage adjustment based on hemoglobin levels (target 10-12 g/dL) to reduce transfusion requirements and improve patients' quality of life.

Chemotherapy-Related Anemia: Based on guidelines such as NICE TA323, EPO can be used to treat chemotherapy-induced anemia; however, the risk-benefit ratio should be carefully assessed in potentially curative chemotherapy regimens.

Neuroprotection and Tissue Repair: EPO-derived peptides (such as Neuro-EPO, ARA290, etc.) have demonstrated neuroprotective activity in animal models of ischemic stroke, Alzheimer's disease, and peripheral nerve injury through multiple pathways, including upregulating Bcl-2, inhibiting caspase-3 activation, and maintaining mitochondrial integrity.

 

Why Choose Our Branded EPO?

As a leading source manufacturer in the industry, we are committed to providing top-tier recombinant protein products to global research and pharmaceutical clients. Our core competitive advantages include:

Direct supply from the source factory: Leveraging our independently established mammalian cell expression platform and purification workshop, we achieve end-to-end production from the construction of genetically engineered bacteria/cell lines to finished product filling, eliminating intermediary markups and offering highly competitive prices.

Professional production equipment: Equipped with internationally advanced bioreactors, AKTA purification systems, and aseptic filling lines, we operate strictly according to GMP standards, ensuring high protein expression levels and high recovery rates.

Stable and reliable quality: Each batch of product undergoes rigorous SDS-PAGE and HPLC purity testing, as well as in vivo/in vitro biological activity verification (such as TF-1 cell proliferation experiments or mouse reticulocyte experiments), ensuring extremely low endotoxin levels and high batch-to-batch activity consistency.

Stable and efficient supply: With a comprehensive large-scale production capacity and cold chain logistics system, we can guarantee continuous supply for bulk purchases, meeting our clients' long-term R&D and production needs.

 

 

Storage and Handling Guidelines

EPO is a highly active protein preparation. Proper storage and handling are crucial to maintaining its biological activity:

Storage Conditions:

Unopened preparations should be strictly stored at 2–8°C, protected from light, and refrigerated. Freezing or vigorous shaking is strictly prohibited.

Under these conditions, the shelf life is typically 24–36 months (refer to the package insert for specific details).

Handling Instructions:

Reconstitution/Dilution: Lyophilized powder must be slowly dissolved by injection using the provided sterile solvent; liquid formulations can be used directly. If dilution is required, use only physiological saline and do not mix with other drugs for infusion.

Usage Time: It is recommended to use immediately after opening. If immediate use is not possible, it can be stored at 2–8°C, but must be used within 24 hours.

Appearance Inspection: Normally, it should be a colorless to slightly yellowish clear liquid or loose substance. If turbidity, precipitation, foreign matter, or abnormal color is found, do not use.

 

 

FAQ
Q: Where is your product manufactured? A: Our products are from Shenzhen, China.

Q: What is the minimum order quantity?

A: The minimum order quantity is 10 bottles/set.

Q: How long does it take to ship?

A: In-stock orders will be shipped within 24 hours.

Q: What purity level can you provide?

A: Standard purity 99%.

Q: Which courier service do you use?

A: FedEx, DHL, UPS, and postal services are available.

Q: How long does shipping take?

A: Approximately 10-15 days.

Q: Can you provide a COA (Certificate of Authorization) quality inspection report and HPLC (High-Performance Computing) report?

A: Yes, all goods undergo professional testing before shipment.

Q: Do you support OEM/ODM?

A: OEM/ODM service is supported, subject to the minimum order quantity requirement.

Q: What are the after-sales service procedures?

A: After the customer signs for the goods, if it is confirmed that the quality problem is caused by our production, they can enjoy free replacement or refund. We uphold a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and making every effort to protect the rights and interests of our clients.

Q: What payment methods are available?

A: We support bank transfers, Bitcoin, Transferwise, and Xoom.

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