Application Methods
5-Amino-1MQ is currently primarily used as a research compound and experimental therapy. Its application is mainly based on preclinical studies and early exploratory protocols:
Routine of Administration: In animal model studies, subcutaneous injection (SC) or intraperitoneal injection (IP) is commonly used; in some exploratory human applications, oral capsules are also available.
Dosage Reference: In diet-induced obesity (DIO) mouse models, the effective intervention dose is typically 20 mg/kg daily. In early human experimental protocols, the common reference dose range is 50 mg to 100 mg daily.
Intervention Cycle: A cyclical dosing strategy (e.g., continuous use for 8 to 12 weeks followed by a 4-week rest period) is generally recommended to prevent receptor desensitization and allow the body's natural NNMT function reset.
Application Scenarios
With its unique cellular metabolic regulation mechanism, 5-Amino-1MQ has broad application prospects in basic medical and translational research:
Obesity and Metabolic Syndrome Research: Used to explore the molecular mechanisms by which NNMT inhibition reverses diet-induced obesity, reduces white adipose tissue (WAT) volume, and improves overall energy expenditure.
Anti-aging and Longevity Medicine: As an NAD+ booster, it is used to investigate its protective effects in delaying cellular senescence, improving mitochondrial dysfunction, and activating the Sirtuins longevity pathway.
Auxiliary Oncology Research: Due to the abnormally high expression of NNMT in various malignant tumors (such as ovarian cancer and breast cancer), 5-Amino-1MQ is used to evaluate its potential as an anti-tumor metabolic regulator, inhibiting tumor metastasis and growth.
Muscle Atrophy and Damage Repair: Exploring its therapeutic potential in improving age-related sarcopenia and promoting muscle stem cell fusion and regeneration.
Storage Conditions
Freeze-dried powder/crystallization (long-term): -20℃ (preferred) or -80℃, sealed, protected from light and moisture; stable for ≥12 months.
Short-term/daily use: Refrigerate at 2–8℃, sealed in the original bottle, protected from light and dry.
Reconstituted solution: Can be stored at 2–8℃ for 2–4 weeks; for long-term storage, please repackage and freeze at -20℃/-80℃, avoiding repeated freeze-thaw cycles.
Oral capsules (finished product): Store in a dry, light-protected place at 15–25℃, do not refrigerate (to prevent moisture absorption by the capsules).
Packaging: Amber bottle/aluminum foil bag, away from metal ions, strong acids and alkalis, and direct sunlight.
FAQ
Q: What is the minimum order quantity?
A: The minimum order quantity is 10 bottles/set.
Q: How long does it take to ship?
A: In-stock orders will be shipped within 24 hours.
Q: What purity can you provide?
A: Standard purity 99%. Q: Which courier service do you use?
A: You can choose FedEx, DHL, UPS, or postal services.
Q: How long does shipping take?
A: Approximately 10-15 days.
Q: Can you provide a COA (Certificate of Account) quality inspection report and HPLC (High-Performance Computing) report?
A: Yes, all goods undergo professional testing before shipment.
Q: Do you support OEM branding?
A: We support OEM branding services, subject to minimum order quantity requirements.
Q: What are your after-sales service details?
A: After the customer receives the goods, if the quality problem is confirmed to be caused by our production, they can enjoy free replacement or refund. We adhere to a pragmatic and responsible service principle, actively responding to and properly handling all kinds of issues, without shirking responsibility or avoiding problems, and fully protecting customer rights.
Q: What payment methods are available?
A: We support bank transfer, Bitcoin, Transferwise, and Xoom.
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