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Survodutide 10mg/vial Promotes Lipid Oxidation And Increases Energy Expenditure. CAS: 2805997-46-8

Survodutide 10mg/vial Promotes Lipid Oxidation And Increases Energy Expenditure. CAS: 2805997-46-8

Survodutide (BI 456906) is an investigational, once-weekly subcutaneous drug that acts as a dual agonist of the glucagon and GLP-1 receptors. It is designed to combine the appetite-suppressing effects of GLP-1 with the glucagon-mediated promotion of energy expenditure and regulation of hepatic fat metabolism, thereby improving metabolic health while facilitating weight loss. According to Phase III clinical data published in the *New England Journal of Medicine*, the drug achieved a maximum weight reduction of 16.6% over 76 weeks and significantly reduced visceral and hepatic fat.

Product Introduction

Application Scenarios
Obesity/Overweight Management: Suitable for overweight or obese adults with a BMI ≥ 27 kg/m², particularly those requiring long-term weight management and seeking to improve metabolic markers; the SYNCHRONIZE Phase III clinical trial series has demonstrated significant weight loss efficacy.
Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD/MASH): Targeted at MASH patients with liver fibrosis (stages F1–F4), including those with compensated cirrhosis; the LIVERAGE Phase III clinical trial series is currently evaluating its efficacy in improving liver fat, inflammation, and fibrosis.
Scientific Research and Raw Material Supply: As a high-purity peptide raw material, it is suitable for research institutions and pharmaceutical companies conducting mechanistic studies on metabolic diseases, formulation development, and preclinical trials; customized specifications are available.

 

 


Potential Benefits in Bodybuilding
Survodutide's dual mechanism offers unique advantages in bodybuilding, centered on "targeted fat loss while preserving muscle":
Highly Efficient Fat Loss: Data from the SYNCHRONIZE-1 Phase III trial show that 76 weeks of treatment resulted in an average weight loss of 16.6%, with visceral fat reduced by 34% and liver fat by 63.1%; weight loss was primarily derived from adipose tissue rather than muscle.
Muscle Preservation: Traditional weight loss methods often result in a 15–60% loss of lean body mass, whereas the highest-dose group in the Survodutide trial experienced a lean body mass loss of less than 10.8%. This maximizes muscle retention, which is crucial for bodybuilders to maintain basal metabolic rate, physical function, and competitive form.
Metabolic Optimization: Activates GCG receptors to boost energy expenditure while improving metabolic markers such as insulin resistance and triglyceride levels, helping athletes maintain physical stamina and metabolic health during fat-loss phases.

 

 

 

Storage and Usage Instructions
Storage Conditions:
Powder form: Store in a sealed container away from light; stable for 3 years at -20°C or 2 years at 4°C.
After reconstitution: Store in aliquots; stable for 6 months at -80°C or 1 month at -20°C; avoid repeated freeze-thaw cycles.
Shipping Method: Transported at low temperatures using ice packs or dry ice to ensure product activity. Usage Notes:
For research use only. Reconstitute under aseptic conditions using sterile water for injection or bacteriostatic water; avoid vigorous shaking to prevent protein denaturation.
For clinical applications, subcutaneous injection once weekly is recommended; dosage should be titrated based on individual patient needs, following specific research protocols or medical advice.

 

 


Why Choose Us?
Direct Manufacturer, Cost-Effective: As the direct manufacturer of Survodutide raw material, we eliminate intermediaries and offer scalable supply-from grams to kilograms-at competitive prices, making us ideal for long-term partnerships and bulk procurement.
Professional Equipment & Mature Processes: We operate GMP-compliant peptide synthesis and purification lines. Utilizing solid-phase synthesis combined with High-Performance Liquid Chromatography (HPLC) purification, we ensure product purity ≥98.0% and single impurity levels ≤2.0%, with acetate and moisture content meeting pharmacopoeial standards.
Stable Supply & Rapid Response: We maintain ample stock and support customized specifications (mg, g, kg). Orders are shipped promptly upon confirmation, with global logistics partnerships ensuring timely delivery to meet urgent research and production needs.
High Purity & Consistent Quality: Each batch comes with a Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and HPLC chromatogram. Purity is verified by third-party testing, and high batch-to-batch consistency ensures reproducible experimental or production results.
After-Sales Support & Technical Assistance: We provide professional technical consultation, including reconstitution methods, storage recommendations, and application protocols. We offer unconditional returns or exchanges for quality issues and provide comprehensive service to ensure customer peace of mind.

 

 


FAQ
Q: Where are you located?
A: Our products originate from Shenzhen, China.
Q: What is the minimum order quantity (MOQ)?
A: The minimum order quantity is 10 vials/sets.
Q: How soon do you ship?
A: Orders for in-stock items are shipped within 24 hours.
Q: What purity levels do you offer?
A: Standard purity is 99%.
Q: Which shipping carriers do you use?
A: Options include FedEx, DHL, UPS, and postal services.
Q: How long does shipping take?
A: Approximately 10–15 days. Q: Can you provide a COA (Certificate of Analysis) and an HPLC test report?
A: Yes, we can provide them; all products undergo professional testing prior to shipment.
Q: Do you offer OEM/private label services?
A: Yes, OEM/private label services are available, subject to minimum order quantity (MOQ) requirements.
Q: How do you handle after-sales issues?
A: If a quality issue attributable to our production is confirmed after the customer receives the goods, we offer free replacement or a refund. We are committed to a pragmatic and responsible service approach, actively addressing and properly resolving any issues without evasion or excuses, while fully safeguarding our customers' interests.
Q: What payment methods do you accept?
A: We accept bank transfers, Bitcoin, TransferWise, and Xoom.

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