Liraglutide is a long-acting GLP-1 homologous polypeptide, available in both medical injectable formulations and research lyophilized powders. It's essential for metabolic, weight loss, and diabetes-related cell and animal experiments. Unlike short-acting GLP-1 reagents, it's fatty acid-modified, resulting in a longer retention time in the body. It can regulate blood sugar and intervene in fat accumulation, making it particularly popular in research on obesity, insulin resistance, and pancreatic protection. Many glucose and lipid metabolism controlled experiments use it as a positive control.
Core Advantages and Functions
Intelligent Blood Sugar Control: It's glucose-dependent, stimulating insulin and inhibiting glucagon only when blood sugar is high; it remains dormant when blood sugar is normal. The risk of hypoglycemia is very low for single-use, making it much more convenient than insulin.
Eating-Controlling Weight Loss: It directly acts on the hypothalamus's appetite center, reducing hunger. Combined with delayed gastric emptying, it prolongs the feeling of fullness after eating, leading to weight and waist circumference reduction.
Cardiovascular Benefits: For type 2 diabetics with coexisting cardiovascular disease, it can reduce the risk of myocardial infarction and stroke, going beyond simply lowering blood sugar.
Long-lasting and Convenient: Long half-life, once-daily subcutaneous injection, can be given before or after meals, making the timing easy to maintain.
Storage Conditions:
Unopened: Must be refrigerated at 2℃–8℃. Never place it against the back wall or freeze it; freezing will destroy its activity, and it must be discarded.
First Opening/In Use: Can be refrigerated or stored at room temperature below 30℃, protected from light (remember to cap the pen). Regardless of the method, it is only for 30 days (1 month). Even if there is any left over, it must be discarded after this period; do not overuse it.
Details: The needle must be removed before storing after each injection to prevent leakage, contamination, and air bubbles affecting the dosage.
Precautions
Gastrointestinal upset: Nausea, vomiting, diarrhea, and loss of appetite are common at the beginning, and usually subside within a few weeks. However, if vomiting is severe or there is persistent, intense upper abdominal pain (be alert for pancreatitis), do not try to tough it out; see a doctor immediately.
Absolute contraindications: Contraindicated in individuals with a personal/family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2); also avoid use if allergic to any of the ingredients. This is not insulin and cannot treat type 1 diabetes or ketoacidosis.
Use with caution in special populations: Not recommended for pregnant or breastfeeding women or those under 18 years of age; those with severe liver or kidney problems or a history of pancreatitis should consult a doctor before use.
Injection precautions: Use subcutaneously (abdomen, thigh, upper arm), not intravenously or intramuscularly; vary the injection site, avoid repeatedly injecting into the same spot; when used in combination with sulfonylurea hypoglycemic agents, the risk of hypoglycemia increases, and dosage adjustments may be necessary.
Appearance inspection: The solution should be colorless and clear. If it becomes cloudy, discolored, or contains particles, discard it immediately, don't hesitate. To be honest, this medication is a "tough nut to crack" among prescription drugs. Never buy or administer it haphazardly on your own. It must be evaluated and approved by an endocrinologist before use to ensure safety and effectiveness.
Hot Tags: liraglutide, a high-quality peptide from china, 5mg/vial, China liraglutide, a high-quality peptide from china, 5mg/vial manufacturers, suppliers, factory
